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KMID : 0388220130200050319
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Journal of the Korean Rheumatism Association
2013 Volume.20 No. 5 p.319 ~ p.322
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A Case of Sjogren’s Syndrome Associated with Neuromyelitis Optica
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Kim Kyung-Han
Park Su-Min
Kim Bo-Sung
Han Seung-Hee
Lee Sang-Yeob
Chung Won-Tae
Lee Sung-Won
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Abstract
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Neuromyelitis optica (NMO) is an idiopathic inflammatory demyelinating disease, characterized by optic neuritis and myelitis. NMO is a very uncommon and serious neurologic manifestation of Sjogren’s syndrome. We report on a 32-year-old female with NMO as central nerve system in-volvement of Sjogren’s syndrome. She had a transverse myelitis ten years ago and did not have symptoms for a long period of time. She visited the emergency center be-cause of worsening weakness of both limbs. She had an appendectomy three days ago before hospitalization. Cervical spinal magnetic resonance imaging showed in-creased signal intensity in T2-weighted images from the cervical (C2) to the upper thoracic (T4) spinal cord. As serum NMO-IgG was positive, we diagnosed neuromyelitis optica and treated with high dose steroid, but failed. Therefore, we treated with plasmapheresis and the patient was discharged without any neurological deficits.
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KEYWORD
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Sjogren’s syndrome , Neuromyelitis optica
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